Search on: CHLORIDE, METHACHOLINE 
Descriptors Found: 1
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Descriptor English:   Methacholine Chloride 
Descriptor Spanish:   Cloruro de Metacolina 
Descriptor Portuguese:   Cloreto de Metacolina 
Synonyms English:   2-(Acetyloxy)-N,N,N-trimethyl-1-propanaminium Chloride
Acetyl-2-methylcholine Chloride
Acetyl-beta-methacholine Chloride
Acetyl-beta-methylcholine
Mecholine
Mecholyl
Provocholine
Provokit
Acetyl 2 methylcholine Chloride
Acetyl beta methacholine Chloride
Acetyl beta methylcholine
Chloride, Methacholine
Methacholine  
Tree Number:   D02.092.877.883.555.500
D02.675.276.534.500
Definition English:   A quaternary ammonium parasympathomimetic agent with the muscarinic actions of ACETYLCHOLINE. It is hydrolyzed by ACETYLCHOLINESTERASE at a considerably slower rate than ACETYLCHOLINE and is more resistant to hydrolysis by nonspecific CHOLINESTERASES so that its actions are more prolonged. It is used as a parasympathomimetic bronchoconstrictor agent and as a diagnostic aid for bronchial asthma. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1116) 
Pharmacological Action:   Bronchoconstrictor Agents
Miotics
Muscarinic Agonists
Parasympathomimetics
 
History Note English:   91 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
EC economics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   29044 
Unique Identifier:   D016210 

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